What's tested

What We Measure

We analyze your gut health across three critical pillars, plus a full microbiome map and parasite screen.

1. Digestion & Absorption

  • Pancreatic Elastase-1: Are you producing enough enzymes to break down that 200g of protein, or is it rotting in your colon?
  • H. pylori context / Protein Breakdown Products: Byproducts of protein that ferments instead of absorbing.
  • Fecal Fats: Are you absorbing the dietary lipids required to synthesize steroid hormones? (Triglycerides, Long-Chain Fatty Acids, Cholesterol, Phospholipids.)

2. Inflammation & Immunology

  • Calprotectin: The gold standard for detecting "silent" inflammation that drives systemic cortisol and kills recovery.
  • Secretory IgA (sIgA): A marker of your mucosal immune system. Low levels indicate "mucosal burnout" often caused by overtraining and chronic stress.
  • Eosinophil Protein X (EPX): Allergic and immune-driven inflammation.
  • Fecal Occult Blood: Hidden blood in the stool.

3. The Gut Microbiome

  • Metabolic Indicators: Levels of Akkermansia muciniphila (linked to leanness and insulin sensitivity) and Faecalibacterium prausnitzii (anti-inflammatory).
  • Short-Chain Fatty Acids (SCFAs): We measure Butyrate production, the fuel for your gut lining and a potent regulator of systemic metabolism.
  • Pathogens: Comprehensive detection of parasites, worms, pathogenic bacteria (like Klebsiella or Salmonella), and yeast/fungi (like Candida).
Parasite & Pathogen Screening

Most gut panels stop at bacteria. This one doesn't. We run a dedicated parasitology workup that most testing skips:

  • Microscopic Ova & Parasite (O&P): screens for roundworms (hookworm, Ascaris, pinworm, Strongyloides, whipworm), tapeworms, flukes, and protozoa.
  • PCR Parasitology: Blastocystis spp., Cryptosporidium, Cyclospora cayetanensis, Dientamoeba fragilis, Entamoeba histolytica, and Giardia.
  • Bacterial & fungal cultures with natural and prescriptive sensitivity panels, so you and your provider know what actually works against what's found.
Full Biomarker Panel

This is what a comprehensive gut map looks like: 24 commensal species across 7 phyla, a full parasite and pathogen screen, plus the core digestion, inflammation, and metabolite biomarkers.

Digestion & Absorption: Pancreatic Elastase-1 · Products of Protein Breakdown (Valerate, Isobutyrate, Isovalerate) · Fecal Fat Total (Triglycerides, Long-Chain Fatty Acids, Cholesterol, Phospholipids)

Inflammation & Immunology: Calprotectin · Eosinophil Protein X (EPX) · Fecal Secretory IgA · Fecal Occult Blood

Metabolites: Short-Chain Fatty Acids Total (Acetate, n-Butyrate, Propionate) · n-Butyrate concentration & % · Beta-glucuronidase

Commensal Microbiome (DNA/PCR) — 24 species across 7 phyla:

  • Bacteroidetes: Bacteroides uniformis, Phocaeicola vulgatus, Barnesiella spp., Odoribacter spp., Prevotella spp.
  • Firmicutes: Anaerotruncus colihominis, Butyrivibrio crossotus, Clostridium spp., Coprococcus eutactus, Faecalibacterium prausnitzii, Lactobacillus spp., Pseudoflavonifractor spp., Roseburia spp., Ruminococcus bromii, Veillonella spp.
  • Actinobacteria: Bifidobacterium spp., Bifidobacterium longum, Collinsella aerofaciens
  • Proteobacteria: Desulfovibrio piger, Escherichia coli, Oxalobacter formigenes
  • Euryarchaeota: Methanobrevibacter smithii
  • Fusobacteria: Fusobacterium spp.
  • Verrucomicrobia: Akkermansia muciniphila

Cultures & Sensitivities: Bacterial culture (commensal + potential pathogens incl. Klebsiella, Salmonella, Shigella, Enterococcus) · Yeast/fungal culture (incl. Candida) · natural + prescriptive antimicrobial/antifungal sensitivities

Parasitology: Microscopic O&P (roundworms, tapeworms, flukes, protozoa) · PCR protozoa panel (Blastocystis, Cryptosporidium, Cyclospora, Dientamoeba fragilis, Entamoeba histolytica, Giardia)

Functional Scores: Maldigestion · Inflammation · Dysbiosis · Metabolite Imbalance · Infection · Inflammation-Associated Dysbiosis (IAD) & Methane Dysbiosis scores

Sample Collection

This is an at-home stool test. You will receive a kit with detailed instructions. You collect the sample in the privacy of your home and ship it back in the pre-paid envelope.

See Stool Sample Collection Instructions

Lab panel details

  • Sample type: Stool

  • HSA/FSA: Accepted

  • Results: Emailed to you

  • Preparation: Fasted (8-12hrs)

  • Meets treatment requirements: Yes

How it works

Purchase your tests

Purchase this test and any other tests you'd like online. A healthcare provider will review and approve your test requests; no healthcare provider visit is required.

Provide your sample

A collection kit will be mailed directly to you. Follow the included instructions to provide your sample, then ship it back to our lab using the prepaid return packaging.

Get your results

Our partnered facilities will process your lab work. Test results typically arrive within 14 business days, and you'll receive an email as soon as they arrive.

Lab panels designed by Board Certified Medical Practitioners

All of our expertly built lab panels are designed by a team of Board Certified Medical Practitioners who lead the charge in preventative medicine.

More expert built panels

Lab work FAQs

Please read our FAQs page to find out more.

How soon do I need to return my specimen samples?

Plan to complete your collection early in the work week and be sure to ship your pack within 24 hours of collection to ensure specimens are viable.

You should also note that some collection packs contain materials that expire (this date is printed on the box label). Plan to collect and return your pack well before that date or within 45 days of receiving the collection pack, whichever comes first. If the pack is not returned within this timeline, we may not be able to complete your test.

How quickly will my lab results arrive?

Your lab results will typically arrive within two weeks, though processing time may vary based on the size and complexity of your panel. Rest assured, once your results are ready, they will be securely delivered to your email.

Does Marek Diagnostics accept insurance?

Marek Diagnostics is a cash-pay service. Our platform offers direct access to comprehensive testing without the limitations, denials, or delays imposed by insurance companies. If traditional insurance covered the kind of proactive, high-quality lab work we offer, Marek Diagnostics wouldn’t need to exist. 

However, many clients successfully use their HSA/FSA to cover their testing costs. Marek Diagnostics is partnered with TrueMed for convenient deployment of HSA/FSA funds at checkout.

Why can’t I order labs in New York, New Jersey, or Rhode Island?

Due to state regulations, Quest services are not available to residents of NY, NJ, or RI when ordered through our platform. If your address is in one of these states, you'll be notified at checkout and won’t be able to complete your order for restricted items.

You can still purchase:

  • Supplements, apparel, and other non-lab items

Not sure which items are restricted? The checkout system will alert you automatically, or you can contact our team for assistance.

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