Diagnostic Blood Test:

• Alkaline Phosphatase (ALP) Total
• Alkaline Phosphatase (ALP) Liver Fraction
• Alkaline Phosphatase (ALP) Bone Fraction
• Alkaline Phosphatase (ALP) Intestinal Fraction

Alkaline phosphatase (ALP) is an enzyme located primarily in the liver and bones. High levels can indicate liver disease or bone growth, while low levels may signal a zinc deficiency.

Alkaline Phosphate (ALP) Isoenzymes testing measures the specific forms of the ALP enzyme found in the liver, bones, and intestines. By distinguishing between the different isoenzymes, this test provides detailed insights into the source of abnormal ALP levels, enabling more accurate diagnosis and targeted treatment.

Liver Isoenzyme: The liver isoenzyme of ALP is primarily associated with liver function. Elevated levels may indicate liver diseases such as hepatitis, cirrhosis, bile duct obstruction, or liver cancer. Monitoring liver ALP isoenzymes is essential for diagnosing and managing hepatic conditions, assessing liver health, and guiding appropriate therapeutic interventions.

Bone Isoenzyme: The bone isoenzyme of ALP reflects bone metabolism and turnover. Increased levels can be seen in conditions involving high bone activity, such as Paget’s disease, osteomalacia, bone fractures, or bone cancers. This measurement is particularly useful in evaluating bone growth in children and adolescents, as well as in diagnosing and monitoring bone-related disorders in adults.

Intestinal Isoenzyme: The intestinal isoenzyme of ALP is linked to digestive health. Elevated levels may suggest conditions affecting the intestines, such as inflammatory bowel disease (IBD), celiac disease, or intestinal tumors. Assessing intestinal ALP isoenzymes aids in diagnosing gastrointestinal disorders, evaluating nutrient absorption, and managing digestive health effectively.